Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep585 | Diabetes therapy | ECE2017

The decreased adiponectin level after the treatment with glibenclamide is associated with deterioration of left ventricular function

Emini Merita , Haliti Edmond , Car Nikica , Begolli Luljeta , Ahmeti Artan , Bajraktari Gani

Background and aim: Hyperglycemia is an important pathogenetic factor, which causes abnormalities at the cardiac myocyte level, leading to structural and functional abnormalities and diabetic cardiomyopathy (DCM). It has been proposed that DCM could also occur as a consequence of other metabolic alterations. Adiponectin concentration is negatively associated with obesity, insulin resistance (IR), oxidative stress and endothelial dysfunction. It can be considered as a predictiv...